Bartolo Colon #40 of the New York Mets pitches in the first inning (Jim McIsaac/Getty Images)

Neil Walker and Michael Conforto gave the Mets an immediate jolt in their return from nagging injuries, and Bartolo Colon pitched New York to a 6-4 victory over the Pittsburgh Pirates on Thursday night.

Curtis Granderson set a Mets record for leadoff homers, while Walker also went deep and had three RBIs against his former team after missing the previous three games with a sore lower back.

Conforto, who hadn't started since Saturday, landed right on his ailing left wrist when he saved a run with a sensational diving catch in the first inning. Showing no ill effects, the left fielder followed Walker's two-run shot in the third inning with a home run of his own to snap a 5-for-54 slump.

Colon (6-3) doubled and scored earlier in the inning on Yoenis Cespedes' deep sacrifice fly, drawing a happy roar from the crowd of 33,052 following his jaunt around the bases.

All three Mets homers came off Juan Nicasio (5-6), who gave up six runs and seven hits in 4 1/3 innings as the Pirates (33-33) fell back to .500 with their seventh loss in eight games.

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