Pope Francis has signed off on the miracle needed to make Mother Teresa a saint, giving the nun who cared for the poorest of the poor one of the Catholic Church's highest honors just two decades after her death.

The Vatican said Friday that Francis approved a decree attributing a miracle to Mother Teresa's intercession during an audience Thursday, his 79th birthday.

No date was set for the canonization, but Italian media have speculated that the ceremony will take place in the first week of September - to coincide with the anniversary of her death, and during Francis' Holy Year of Mercy.

Mother Teresa, a Nobel Peace Prize winner, died on Sept. 5, 1997, at 87.

At the time, her Calcutta, India-based Missionaries of Charity order had nearly 4,000 nuns and ran roughly 600 orphanages, soup kitchens, homeless shelters and clinics around the world.

Mother Teresa, born in Albania as Agnes Gonxha Bojaxhiu in 1910, was beatified in 2003 in Rome after the Vatican said an Indian woman's prayers to the nun rid her of an incurable tumor.

The miracle needed for her canonization concerned the inexplicable cure in 2008 of a man in Brazil with multiple brain abscesses who, within a day of being in a coma, was cured, according to a report in Avennire, the newspaper of the Italian bishops' conference. The Vatican ascertained that his wife's prayers for Mother Teresa's intercession were responsible, the report said.

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