PHILADELPHIA (AP) -- Pinch-hitter Grady Sizemore hit a go-ahead two-run homer in the sixth inning, helping the Philadelphia Phillies beat the NL East-leading Washington Nationals 8-4 Wednesday night to complete a three-game sweep.

Grady Sizemore #24 of the Philadelphia Phillies hits a two run home run in the sixth inning
Grady Sizemore #24 of the Philadelphia Phillies hits a two run home run in the sixth inning ( Brian Garfinkel/Getty Images)
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Marlon Byrd hit a two-run homer and Jimmy Rollins hit a solo shot to back Kyle Kendrick (7-11). The right-hander allowed four runs and seven hits in six innings.

The last-place Phillies went 7-2 on their best homestand this season.

Denard Span was 3 for 4 and fell a triple short of the cycle for the Nationals. Doug Fister (12-5) allowed a season-high 10 hits and five runs - four earned - in 5 2-3 innings.

The Nationals had won 12 of 13 before losing three in a row in Philadelphia. They still have the best record (75-57) in the NL and a comfortable 6 1/2-game lead over Atlanta in the division.

Byrd started Philadelphia's rally in the sixth with a leadoff single. Domonic Brown lined an RBI double to right-center to cut the deficit to 4-3. Two outs later, Sizemore drove an 0-2 pitch into the right-field seats for a 5-4 lead and his first career pinch homer.

Fister left after hitting the next batter, Ben Revere, with an 89 mph fastball on his right arm. Revere went down in pain, but stayed in the game.

Byrd connected off Ross Detwiler in the seventh for his team-high 24th homer.

The Nationals took a 3-2 lead in the third when Jayson Werth singled in Span, who led off the inning with a double.

Span ripped a 427-foot homer off the railing in the second deck to make it 4-2 in the fifth. It was Span's second homer this season in his 512th at-bat.

Rollins hit a towering drive into the right field seats for his 17th homer to cut it to 2-1 in the first. Chase Utley followed with a single to center. He scored when Span misplayed Ryan Howard's single. The ball rolled past Span for an error and Howard ended up on second.

Howard added an RBI single in the eighth, finishing 3 for 5.

Before the game, the Phillies hosted Mo'ne Davis and her Taney Dragons teammates in a tribute to the team from the Little League World Series.

TRAINER'S ROOM

Nationals: 1B Adam LaRoche was back in the starting lineup after being held out due to back tightness on Tuesday. He went 0 for 4.

Phillies: OF John Mayberry Jr. (right wrist) is expected to be activated when rosters are expanded Monday. RHP Mike Adams (shoulder) is rehabbing at Triple-A Lehigh Valley and hopes to pitch in September.

UP NEXT

Nationals: RHP Jordan Zimmermann (9-5, 2.93) starts the opener of an interleague series at Seattle. Felix Hernandez, the 2010 AL Cy Young Award winner, goes for the Mariners.

Phillies: RHP David Buchanan (6-7, 4.21) starts the opener of a three-game series at the New York Mets on Friday night. He's 0-2 with a 4.26 ERA against the Mets.

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