Antrel Rolle intercepted two passes by Alex Smith, Prince Amukamara picked off another and the Giants shut down San Francisco in a 26-3 victory over the 49ers on Sunday in a rematch of last season's NFC championship game.

Victor Cruz catches a touchdown pass
Victor Cruz catches a touchdown pass. (Brian Bahr/Getty Images)
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After outscoring the Bills and Jets by a combined 79-3 the last two weeks, the 49ers (4-2) met their match again with Eli Manning. No overtime needed this time, and not much
of Manning either.

Manning threw for 193 yards and one touchdown, Ahmad Bradshaw ran for 116 yards and a score and the Giants (4-2) rode a dominant defense and four field goals by Lawrence Tynes to hand outspoken 49ers coach Jim Harbaugh the most lopsided loss of his tenure.
(Copyright 2012 by The Associated Press.  All Rights Reserved.)

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